@article{ref1,
title="Cognitive performance in a placebo-controlled pharmacotherapy trial for youth with marijuana dependence",
journal="Addictive behaviors",
year="2015",
author="Roten, Amanda and Baker, Nathaniel L. and Gray, Kevin M.",
volume="45C",
number="",
pages="119-123",
abstract="BACKGROUND: Adolescent marijuana use is associated with neurocognitive impairment, but further work is needed to assess the relationship between treatment-associated abstinence and cognitive performance. <br><br>METHODS: This secondary analysis, conducted in the context of a marijuana cessation pharmacotherapy trial in adolescents, examined cognitive performance at baseline and at two time points during treatment using the CNS Vital Signs assessment battery. <br><br>RESULTS: Abstinence from marijuana, relative to continued use, as assessed via urine cannabinoid testing, was associated with significant improvement in composite memory (p<0.001), verbal memory (the most impacted component of composite memory) (p<0.001), and psychomotor performance (p=0.045) scores. <br><br>CONCLUSIONS: These findings suggest that some domains of cognitive performance improve significantly even in the early stages of treatment-associated abstinence.<p /> <p>Language: en</p>",
language="en",
issn="0306-4603",
doi="10.1016/j.addbeh.2015.01.013",
url="http://dx.doi.org/10.1016/j.addbeh.2015.01.013"
}