
@article{ref1,
title="Cannabinoid agonist rescues learning and memory after a traumatic brain injury",
journal="Annals of clinical and translational neurology",
year="2015",
author="Arain, Marium and Khan, Maida and Craig, Laura and Nakanishi, Stan T.",
volume="2",
number="3",
pages="289-294",
abstract="Traumatic brain injury can cause persistent challenges including problems with learning and memory. Previous studies suggest that the activation of the cannabinoid 1 receptor after a traumatic brain injury could be beneficial. We tested the hypothesis that posttraumatic brain injury administration of a cannabinoid 1 receptor agonist can rescue deficits in learning and memory. Young adult male rats were subjected to a moderately severe controlled cortical impact brain injury, with a subset given postinjury i.p. injections of a cannabinoid receptor agonist. Utilizing novel object recognition and the morris water task, we found that the brain-injured animals treated with the agonist showed a marked recovery.<p /><p>Language: en</p>",
language="en",
issn="2328-9503",
doi="10.1002/acn3.163",
url="http://dx.doi.org/10.1002/acn3.163"
}