@article{ref1,
title="Association between adverse childhood experiences in the home and pediatric asthma",
journal="Annals of allergy, asthma and immunology",
year="2015",
author="Wing, Robyn and Gjelsvik, Annie and Nocera, Mariann and McQuaid, Elizabeth L.",
volume="114",
number="5",
pages="379-384",
abstract="BACKGROUND: Numerous studies suggest that psychosocial factors could contribute to pediatric asthma. <br><br>OBJECTIVE: To examine the relation between single and cumulative adverse childhood experiences (ACEs), a measurement of household dysfunction, on parent report of lifetime asthma in children. <br><br>METHODS: This cross-sectional study used data from the 2011 to 2012 National Survey of Children's Health, a nationally representative sample of children 0 to 17 years old (n = 92,472). The main exposure was parent or guardian report of 6 ACE exposures (eg, witnessing domestic violence). The relation between ACE exposures and parent-reported diagnosis of childhood asthma was examined using multivariable logistic regression after controlling for demographic, socioeconomic, and behavioral covariates. <br><br>RESULTS: Overall asthma prevalence was 14.6%. Exposure prevalence to any ACE was 29.2%. Increased number of ACE exposures was associated with increased odds of asthma. In the adjusted model, the odds of reporting asthma were 1.28 (95% confidence interval [CI] 1.14-1.43) for those reporting 1 ACE, 1.73 (95% CI 1.27-2.36) for those with 4 ACEs, and 1.61 (95% CI 1.15-2.26) for those with 5 or 6 ACEs compared with those with no ACE exposures. Effects were moderated by Hispanic ethnicity. Hispanic children exposed to 4 ACEs had a 4.46 times increase in lifetime asthma (95% CI 2.46-8.08); white children had a 1.19 times increase (95% CI 0.80-1.79) compared with those exposed to 0 ACE. <br><br>CONCLUSION: This study supports the growing evidence for the biopsychosocial model of asthma onset. Future studies should examine the association between ACEs and specific asthma-related health outcomes.<p /> <p>Language: en</p>",
language="en",
issn="1081-1206",
doi="10.1016/j.anai.2015.02.019",
url="http://dx.doi.org/10.1016/j.anai.2015.02.019"
}