
@article{ref1,
title="Y chromosome STR typing in crime casework",
journal="Forensic science, medicine, and pathology",
year="2009",
author="Roewer, Lutz",
volume="5",
number="2",
pages="77-84",
abstract="Since the beginning of the nineties the field of forensic Y chromosome analysis has been successfully developed to become commonplace in laboratories working in crime casework all over the world. The ability to identify male-specific DNA renders highly variable Y-chromosomal polymorphisms, the STR sequences, an invaluable addition to the standard panel of autosomal loci used in forensic genetics. The male-specificity makes the Y chromosome especially useful in cases of male/female cell admixture, namely in sexual assault cases. On the other hand, the haploidy and patrilineal inheritance complicates the interpretation of a Y-STR match, because male relatives share for several generations an identical Y-STR profile. Since paternal relatives tend to live in the geographic and cultural territory of their ancestors, the Y chromosome analysis has a potential to make inferences on the population of origin of a given DNA profile. This review addresses the fields of application of Y chromosome haplotyping, the interpretation of results, databasing efforts and population genetics aspects.<p /><p>Language: en</p>",
language="en",
issn="1547-769X",
doi="10.1007/s12024-009-9089-5",
url="http://dx.doi.org/10.1007/s12024-009-9089-5"
}