@article{ref1,
title="Overdose of dolutegravir in combination with tenofovir disaproxil fumarate/emtricitabine in suicide attempt in a 21-year old patient",
journal="AIDS research and therapy",
year="2015",
author="Lee, Marcel and Eyer, Florian and Felgenhauer, Norbert and Klinker, Hartwig Hf and Spinner, Christoph D.",
volume="12",
number="",
pages="18-18",
abstract="A 21 year old MSM patient with newly diagnosed HIV infection was hospitalized in our department after ingestion of an overdose of his antiretroviral therapy (ART) comprising dolutegravir (DTG - Tivicay®) and tenofovir disaproxil fumarate/emtricitabine (Truvada®) in suicidal intention. On admission, the patient did not show any clinical signs of intoxication and laboratory findings were unremarkable. After 6 hours of intensive care monitoring, the patient was referred to a psychiatric clinic. 5 days after the day of intoxication, serum creatinine levels increased to high normal values (1.2 mg/dl). However, levels never exceeded the upper threshold. 8 and 12 weeks later, serum creatinine normalized to levels measured prior to the intoxication. No other adverse events occurred, and the patient does not suffer from permanent impairments.<p /> <p>Language: en</p>",
language="en",
issn="1742-6405",
doi="10.1186/s12981-015-0054-y",
url="http://dx.doi.org/10.1186/s12981-015-0054-y"
}