@article{ref1,
title="Heart rate variability as a predictor of death in injured",
journal="Journal of burn care and research",
year="2015",
author="Loguidice, Michael J. and Schutt, Robert C. and Horton, Jureta W. and Minei, Joseph P. and Keeley, Ellen C.",
volume="37",
number="3",
pages="e227-33",
abstract="Heart rate variability (HRV), a noninvasive technique used to quantify fluctuations in the interval between normal heartbeats, is a predictor of mortality in some patient groups. The aim of this study was to assess HRV in burn trauma patients as a predictor of mortality. The authors prospectively performed 24-hour Holter monitoring on injured and collected demographic information, burn injury details, and in-hospital clinical events. Analysis of HRV in the time and frequency domains was performed. A total of 40 injured with a mean age of 44 ± 15 years were enrolled. Mean %TBSA burn was 27 ± 22% for the overall population and was significantly higher in those who died compared with those who survived (55 ± 23% vs 19 ± 13%; P <.0001). There was a statistically significant inverse linear correlation between SD of NN intervals and %TBSA (r = -.337, R = 0.113, 95% CI = -0.587 to -0.028, two-tailed P =.034), as well as with ultra low frequency power and %TBSA burn (r = -0.351, R = 0.123, 95% CI = -0.152 to -0.009; P =.027). The receiver-operator characteristic showed the area under the curve for %TBSA as a predictor of death was 0.82 (P <.001), for SD of NN interval was 0.94 (P <.0001), and for ultra low frequency power was 0.96 (P <.0001). Deranged HRV in the early postburn period is a strong predictor of death.<p /> <p>Language: en</p>",
language="en",
issn="1559-047X",
doi="10.1097/BCR.0000000000000260",
url="http://dx.doi.org/10.1097/BCR.0000000000000260"
}