@article{ref1,
title="Cardiac dysfunction following brain death after severe pediatric traumatic brain injury: a preliminary study of 32 children",
journal="International journal of critical illness and injury science",
year="2015",
author="Krishnamoorthy, Vijay and Prathep, Sumidtra and Sharma, Deepak and Fujita, Yasuki and Armstead, William and Vavilala, Monica S.",
volume="5",
number="2",
pages="103-107",
abstract="BACKGROUND: Cardiac dysfunction after brain death has been described in a variety of brain injury paradigms but is not well understood after severe pediatric traumatic brain injury (TBI). Cardiac dysfunction may have implications for organ donation in this patient population. <br><br>MATERIALS AND METHODS: We conducted a retrospective cohort study of pediatric patients with severe TBI, both with and without a diagnosis of brain death, who underwent echocardiography during the first 2 weeks after TBI, between the period of 2003-2011. We examined cardiac dysfunction in patients with and without a diagnosis of brain death. <br><br>RESULTS: In all, 32 (2.3%) of 1,413 severe pediatric TBI patients underwent echocardiogram evaluation. Most patients had head abbreviated injury score 5 (range 2-6) and subdural hematoma (34.4%). Ten patients with TBI had brain death compared with 22 severe TBI patients who did not have brain death. Four (40%) of 10 pediatric TBI patients with brain death had a low ejection fraction (EF) compared with 1 (4.5%) of 22 pediatric TBI patients without brain death who had low EF (OR = 14, P = 0.024). <br><br>CONCLUSIONS: The incidence of cardiac dysfunction is higher among pediatric severe TBI patients with a diagnosis of brain death, as compared to patients without brain death. This finding may have implications for cardiac organ donation from this population and deserves further study.<p /> <p>Language: en</p>",
language="en",
issn="2229-5151",
doi="10.4103/2229-5151.158409",
url="http://dx.doi.org/10.4103/2229-5151.158409"
}