@article{ref1,
title="Falls and fractures 2 years after acute stroke: the North Dublin Population Stroke Study",
journal="Age and ageing",
year="2015",
author="Callaly, E. L. and Ni Chroinin, D. and Hannon, N. and Sheehan, O. and Marnane, M. and Merwick, A. and Kelly, L. A. and Horgan, G. and Williams, Elizabeth and Harris, D. and Williams, D. and Moore, A. and Dolan, E. and Murphy, S. and Kelly, P. J. and Duggan, J. and Kyne, L.",
volume="44",
number="5",
pages="882-886",
abstract="BACKGROUND: Stroke patients are at increased risk of falls and fractures. The aim of this study was to determine the rate, predictors and consequences of falls within 2 years after stroke in a prospective population-based study in North Dublin, Ireland. <br><br>DESIGN: Prospective population-based cohort study. SUBJECTS: 567 adults aged >18 years from the North Dublin Population Stroke Study. <br><br>METHODS: Participants were enrolled from an Irish urban population of 294,592 individuals, according to recommended criteria. Patients were followed for 2 years. Outcome measures included death, modified Rankin Scale (mRS), fall and fracture rate. <br><br>RESULTS: At 2 years, 23.5% (124/522) had fallen at least once since their stroke, 14.2% (74/522) had 2 or more falls and 5.4% (28/522) had a fracture. Of 332 survivors at 2 years, 107 (32.2%) had fallen, of whom 60.7% (65/107) had 2 or more falls and 23.4% (25/107) had fractured. In a multivariable model controlling for age and gender, independent risk factors for falling within the first 2 years of stroke included use of alpha-blocker medications for treatment of hypertension (P = 0.02). When mobility measured at Day 90 was included in the model, patients who were mobility impaired (mRS 2-3) were at the highest risk of falling within 2 years of stroke [odds ratio (OR) 2.30, P = 0.003] and those functionally dependent (mRS 4-5) displayed intermediate risk (OR 2.02, P = 0.03) when compared with independently mobile patients. <br><br>CONCLUSION: Greater attention to falls risk, fall prevention strategies and bone health in the stroke population are required.<p /> <p>Language: en</p>",
language="en",
issn="0002-0729",
doi="10.1093/ageing/afv093",
url="http://dx.doi.org/10.1093/ageing/afv093"
}