@article{ref1,
title="Methodology and preliminary results from the neurobiology of late-life depression study",
journal="International psychogeriatrics / IPA",
year="2015",
author="Steffens, David C. and Manning, Kevin J. and Wu, Rong and Grady, James J. and Fortinsky, Richard H. and Tennen, Howard A.",
volume="27",
number="12",
pages="1987-1997",
abstract="BACKGROUND: We sought to investigate the relationship between neuroticism and depression in an elderly cohort. In this paper, we describe the methods of an National Institute of Mental Health-NIMH-supported study and present findings among the cohort enrolled to date. <br><br>METHODS: We used the NEO Personality Inventory to assess neuroticism, and we employed several cognitive neuroscience-based measures to examine emotional control. <br><br>RESULTS: Compared with a group of 27 non-depressed older control subjects, 33 older depressed subjects scored higher on measures of state and trait anxiety and neuroticism. On our experimental neuroscience-based measures, depressed subjects endorsed more negative words compared with controls on an emotional characterization test. In addition, we found a significant group-by-congruency effect on an emotional interference test where subjects were asked to identify the face's emotional expression while ignoring the words &quot;fear&quot; or &quot;happy&quot; labeled across the face. <br><br>CONCLUSION: Thus, in this preliminary work, we found significant differences in measures of neuroticism and emotional controls among older adults with and without depression.<p /> <p>Language: en</p>",
language="en",
issn="1041-6102",
doi="10.1017/S1041610215001386",
url="http://dx.doi.org/10.1017/S1041610215001386"
}