@article{ref1,
title="Methadone intoxication in a child: toxic encephalopathy?",
journal="Journal of child neurology",
year="2006",
author="Anselmo, M. and Campos Rainho, Antonio and do Carmo Vale, Maria and Estrada, Joao and Valente, Rosalina and Correia, Manuela and Vieira, Jose Pedro and Barata, Deolinda",
volume="21",
number="7",
pages="618-620",
abstract="Methadone is used in the treatment of opioid addiction. Acute intoxication can lead to severe consequences and can even be lethal. In several case reports and small series, a presumably toxic leukoencephalopathy is described resulting from inhalation of heroin. We present the case of a 3-year-old boy who ingested methadone accidentally. In a coma with acute obstructive hydrocephalus owing to massive cerebellar edema and supratentorial lesions, he was successfully treated with methylprednisolone and cerebrospinal fluid external drainage. To our knowledge, this is the first report of an encephalopathy associated with synthetic opioid intoxication.<p /> <p>Language: en</p>",
language="en",
issn="0883-0738",
doi="",
url="http://dx.doi.org/"
}