@article{ref1,
title="Effect of heat waves on morbidity and mortality due to Parkinson's disease in Madrid: a time-series analysis",
journal="Environment international",
year="2016",
author="Linares, Cristina and Martinez-Martin, Pablo and Rodríguez-Blázquez, Carmen and Forjaz, Maria João and Carmona, Rocío and Díaz, Julio",
volume="89-90",
number="",
pages="1-6",
abstract="BACKGROUND: Parkinson's disease (PD) is one of the factors which are associated with a higher risk of mortality during heat waves. The use of certain neuroleptic medications to control some of this disease's complications would appear to be related to an increase in heat-related mortality. <br><br>OBJECTIVE: To analyse the relationship and quantify the short-term effect of high temperatures during heat wave episodes in Madrid on daily mortality and PD-related hospital admissions. <br><br>METHODS: We used an ecological time-series study and fit Poisson regression models. We analysed the daily number of deaths due to PD and the number of daily PD-related emergency hospital admissions in the city of Madrid, using maximum daily temperature (°C) as the main environmental variable and chemical air pollution as covariates. We controlled for trend, seasonalities, and the autoregressive nature of the series. <br><br>RESULTS: There was a maximum daily temperature of 30°C at which PD-related admissions were at a minimum. Similarly, a temperature of 34°C coincides with an increase in the number of admissions. For PD-related admissions, the Relative Risk (RR) for every increase of 1°C above the threshold temperature was 1.13 IC95%:(1.03-1.23) at lags 1 and 5; and for daily PD-related mortality, the RR was 1.14 IC95%:(1.01-1.28) at lag 3. <br><br>CONCLUSION: Our results indicate that suffering from PD is a risk factor that contributes to the excess morbidity and mortality associated with high temperatures, and is relevant from the standpoint of public health prevention plans.<p /> <p>Language: en</p>",
language="en",
issn="0160-4120",
doi="10.1016/j.envint.2016.01.017",
url="http://dx.doi.org/10.1016/j.envint.2016.01.017"
}