@article{ref1,
title="Assessment of depression prevalence and its relation with interleukin 18 one year after renal transplantation",
journal="American journal of therapeutics",
year="2015",
author="Sahraei, Zahra and Eshraghi, Azadeh and Eslami, Neda and Mehdizadeh, Mona",
volume="23",
number="6",
pages="e1579-e1585",
abstract="Renal transplantation is the treatment of choice for many patients with end-stage renal disease. Because there is little information about depression after kidney transplantation, we investigated frequency and determinant factors of depression and also its association with interleukin (IL)-18. Kidney transplant recipients were investigated between January 2011 and February 2013. Depression was assessed using the Beck Depression Inventory (BDI, BDI-II). We investigated the relationship between 1-year posttransplantation depression and all-cause mortality, acute kidney injury, and serum creatinine 1, 3, and 12 months after transplantation. Furthermore, the association of depression with IL-18 biomarker was recorded 1 year after transplantation. A total of 74 patients (age: 37.06 ± 16.2 years; 59.5% male) were enrolled in this study 1 year after transplantation. Nineteen (25.6%), 2 (2.7%), and 1 (1.3%) of them experienced mild, moderate, and severe depression, respectively. IL-18 biomarker (independent variable) was significantly associated with depression 1 year after transplantation. Our data suggested that IL-18 level increased significantly in renal transplant patients with depression.<p /> <p>Language: en</p>",
language="en",
issn="1075-2765",
doi="10.1097/MJT.0000000000000192",
url="http://dx.doi.org/10.1097/MJT.0000000000000192"
}