@article{ref1,
title="Dual task cost of cognition is related to fall risk in patients with multiple sclerosis: a prospective study",
journal="Clinical rehabilitation",
year="2016",
author="Etemadi, Yasaman",
volume="31",
number="2",
pages="278-284",
abstract="OBJECTIVE: To examine whether change in cognitive performance during dual task condition compared with a task in isolation, known as dual task cost, is related to fall risk of patients with multiple sclerosis. <br><br>DESIGN: Prospective cohort. During baseline assessment, data about balance, walking and cognitive performance of patients with multiple sclerosis were collected under a single and dual task condition. The dual task cost was calculated as a percentage of change in parameters from single to dual task conditions. Falls were recorded prospectively for six months and participants were classified as none/one time fallers and recurrent fallers (⩾2 falls). The association between dual task costs and fall status was evaluated by logistic regression. SETTING: Balance research lab of university hospital. PARTICIPANTS: A total of 60 patients with relapsing-remitting multiple sclerosis. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: The dual task cost of the center of pressure sway area, walking velocity and correct response rate were outcome measures for balance, walking and cognitive performance, respectively. <br><br>RESULTS: A total of 79 falls were reported by 38 of the participants who experienced one or more falls; 26 (43.3%) of them had recurrent falls. Dual tasking resulted in increased sway area and decreased walking velocity and correct response rate during walking (all p values <0.05). Logistic regressions showed that the dual task cost of the correct response rate during walking and walking velocity were associated with increased risk of recurrent falls (P = 0.02, odds ratio = 1.34; confidence interval (CI) 1.04-3.74; P =  0.05, odds ratio = 1.23, CI = 1.02-4.45, respectively). <br><br>CONCLUSIONS: The dual task cost of cognition was related to fall, which should be considered as a target for falls evaluation and prevention strategies.<br><br>© The Author(s) 2016.<p /> <p>Language: en</p>",
language="en",
issn="0269-2155",
doi="10.1177/0269215516637201",
url="http://dx.doi.org/10.1177/0269215516637201"
}