@article{ref1,
title="Altered sleep spindle in delayed encephalopathy after acute carbon monoxide poisoning",
journal="Journal of clinical sleep medicine",
year="2016",
author="Yoshiike, Takuya and Nishida, Masaki and Yagishita, Kazuyoshi and Nariai, Tadashi and Ishii, Kenji and Nishikawa, Toru",
volume="12",
number="6",
pages="913-915",
abstract="Delayed encephalopathy (DE) after acute carbon monoxide poisoning causes persistent or delayed cognitive deficits. Although DE affects not only the cerebral white matter and globus pallidus but also the cortex and thalamus, whether these brain lesions alter sleep along with clinical manifestations of DE remains unknown. A 46-year-old man with DE underwent repetitive hyperbaric oxygen therapy. The patient was evaluated by not only neuropsychological and neuroimaging testing but polysomnography (PSG) over the clinical course. Neurological symptoms improved markedly; however, profound frontal cognitive deficits continued. The PSG revealed prolonged absence and delayed recovery of sleep spindles across recordings. Alterations in spindle oscillations in DE could provide further insight into sleep regulatory networks.<br><br>Copyright © 2016 American Academy of Sleep Medicine. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="1550-9389",
doi="",
url="http://dx.doi.org/"
}