@article{ref1,
title="Soluble urokinase plasminogen activator receptor informs on the progression course after multiple injuries",
journal="Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals",
year="2016",
author="Patrani, Maria and Tsaganos, Thomas and Kotzampassi, Katerina and Paraschos, Michael and Katsenos, Chrysostomos and Giamarellos-Bourboulis, Evangelos J. and Mandragos, Konstantinos",
volume="21",
number="7",
pages="660-664",
abstract="PURPOSE: The purpose of this study is to study the use of soluble urokinase plasminogen activator receptor (suPAR) for the prognosis of multiple organ dysfunction (MOF) after multiple traumas. <br><br>METHODS: Serum suPAR was measured within the first 24 h after multiple injuries in 85 patients. Measurements were repeated after 4 d or at sepsis onset. <br><br>RESULTS: Odds ratio for trauma-associated MOF was 4.09 (p: 0.026) with admission suPAR greater than 8 ng/ml. More than 40% increases of suPAR were associated with odds ratio 9.33 (p: 0.047) for severe sepsis. <br><br>CONCLUSIONS: suPAR is a useful surrogate biomarker for development of MOF and severe sepsis after multiple traumas.<p /> <p>Language: en</p>",
language="en",
issn="1354-750X",
doi="10.3109/1354750X.2016.1171911",
url="http://dx.doi.org/10.3109/1354750X.2016.1171911"
}