@article{ref1,
title="Heart rate variability and suicidal behavior",
journal="Psychiatry research",
year="2016",
author="Wilson, Scott T. and Chesin, Megan and Fertuck, Eric and Keilp, John and Brodsky, Beth and Mann, J. John and Sönmez, Cemile Ceren and Benjamin-Phillips, Christopher and Stanley, Barbara",
volume="240",
number="",
pages="241-247",
abstract="Identification of biological indicators of suicide risk is important given advantages of biomarker-based models. Decreased high frequency heart rate variability (HF HRV) may be a biomarker of suicide risk. The aim of this research was to determine whether HF HRV differs between suicide attempters and non-attempters. Using the Trier Social Stress Test (TSST), we compared HF HRV between females with and without a history of suicide attempt, all with a lifetime diagnosis of a mood disorder. To investigate a potential mechanism explaining association between HF HRV and suicide, we examined the association between self-reported anger and HF HRV. <br><br>RESULTS of an Area under the Curve (AUC) analysis showed attempters had a lower cumulative HF HRV during the TSST than non-attempters. In addition, while there was no difference in self-reported anger at baseline, the increase in anger was greater in attempters, and negatively associated with HF HRV. <br><br>RESULTS suggest that suicide attempters have a reduced capacity to regulate their response to stress, and that reduced capacity to regulate anger may be a mechanism through which decreased HF HRV can lead to an increase in suicide risk. Our results have implications for the prevention of suicidal behavior in at-risk populations.<br><br>Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="0165-1781",
doi="10.1016/j.psychres.2016.04.033",
url="http://dx.doi.org/10.1016/j.psychres.2016.04.033"
}