@article{ref1,
title="Sex differences in the relationship between heavy alcohol use, inhibition and performance monitoring: disconnect between behavioural and brain functional measures",
journal="Psychiatry research",
year="2016",
author="Smith, Janette L. and Iredale, Jaimi M. and Mattick, Richard P.",
volume="254",
number="",
pages="103-111",
abstract="Previous research has reported mixed evidence of sex differences in the relationship between heavy alcohol use and deficits in behavioural control. Here, we examine sex differences in behavioural and event-related potential (ERP) markers of deficient inhibition. Participants were 71 young adults aged 18-21, who either drank heavily regularly (i.e., four standard drinks on one occasion, at least once a month, n=33, 20 male) or drank heavily less often than this (including never, n=38, 21 male). They completed a stop-signal task while ERPs were recorded. Increases in stop-signal reaction time, the time required to stop a response, were related to heavy drinking only in female participants. P3 amplitude, ERN amplitude and ERN latency did not display a significant interaction between group and sex. Heavy drinkers, regardless of sex, displayed a marginally larger successful>failed effect for P3 amplitude, and a marginally smaller error-related negativity. An apparent disconnect exists in behavioural and psychophysiological measures of sex differences in the relationship between heavy alcohol consumption and inhibitory processing; male heavy drinkers display only psychophysiological but not behavioural deficits, while female heavy drinkers display both. Future research may determine whether sex differences are apparent for other substances besides alcohol.<br><br>Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="0165-1781",
doi="10.1016/j.pscychresns.2016.06.012",
url="http://dx.doi.org/10.1016/j.pscychresns.2016.06.012"
}