@article{ref1,
title="Comparative risk of hip fractures in elderly nursing home patients with depression using paroxetine and other selective serotonin reuptake inhibitors",
journal="Journal of comparative effectiveness research",
year="2016",
author="Bali, Vishal and Chatterjee, Satabdi and Johnson, Michael L. and Chen, Hua and Carnahan, Ryan M. and Aparasu, Rajender R.",
volume="5",
number="5",
pages="461-473",
abstract="AIM: To evaluate comparative safety of paroxetine and other selective serotonin reuptake inhibitors (SSRIs) for the risk of hip fractures. Patients & methods: A propensity score-matched retrospective cohort study was conducted using 2007-2010 Minimum Data Set linked Medicare data. Robust Cox proportional hazards model was used to evaluate the risk of hip fractures in depressed elderly nursing home residents. <br><br>RESULTS: Cox analysis did not find any significant difference in the risk of hip fractures for the paroxetine users (hazard ratio: 1.09; 95% CI: 0.91-1.32) when compared with other SSRIs. <br><br>RESULTS from the sensitivity analysis supported the main findings. <br><br>CONCLUSION: There was no differential risk of hip fractures between paroxetine and other SSRIs. Future studies are needed to evaluate other anticholinergic effects of paroxetine.<p /> <p>Language: en</p>",
language="en",
issn="2042-6305",
doi="10.2217/cer-2016-0009",
url="http://dx.doi.org/10.2217/cer-2016-0009"
}