@article{ref1,
title="Concussions, traumatic brain injury, and the innovative use of omega-3s",
journal="Journal of the American College of Nutrition",
year="2016",
author="Lewis, Michael D.",
volume="35",
number="5",
pages="469-475",
abstract="Traumatic brain injury (TBI), with its diverse heterogeneity and prolonged secondary pathogenesis, remains a clinical challenge. Clinical studies thus far have failed to identify an effective treatment strategy when a combination of targets controlling aspects of neuroprotection, neuroinflammation, and neuroregeneration is needed. Omega-3 fatty acids (n-3FA) offer the advantage of this approach. Although further clinical trial research is needed, there is a growing body of strong preclinical evidence and clinical experience that suggests that benefits may be possible from aggressively adding substantial amounts of n-3FA to optimize the nutritional foundation of TBI, concussion, and postconcussion syndrome patients. Early and optimal doses of n-3FA, even in a prophylactic setting, have the potential to improve outcomes from this potentially devastating problem. With evidence of unsurpassed safety and tolerability, n-3FA should be considered mainstream, conventional medicine, if conventional medicine can overcome its inherent bias against nutritional, nonpharmacologic therapies.<p /> <p>Language: en</p>",
language="en",
issn="0731-5724",
doi="10.1080/07315724.2016.1150796",
url="http://dx.doi.org/10.1080/07315724.2016.1150796"
}