@article{ref1,
title="The fluoxetine and suicide controversy : a review of the evidence",
journal="CNS drugs",
year="1994",
author="Healy, D.",
volume="1",
number="3",
pages="223-231",
abstract="Evidence is emerging that a range of psychotropic drugs may precipitate akathisia and/or panic reactions in predisposed patients. The use of fluoxetine has hitherto been the most notable example of this occurrence. These reactions may foster the genesis of suicidal ideation in a small proportion of patients. At present, it is not clear what biological mechanism may underlie this finding. The serotonin (5-hydroxytryptarnine; 5-HT) system may be involved in these reactions.The best management of such reactions will involve counselling patients beforehand about the possibility of these reactions, stopping treatment with the agents if such a reaction is suspected, or adding an agent with 5-HT1A antagonistic properties (e.g. propranolol) to the treatment regimen.<p /> <p>Language: en</p>",
language="en",
issn="1172-7047",
doi="10.2165/00023210-199401030-00007",
url="http://dx.doi.org/10.2165/00023210-199401030-00007"
}