@article{ref1,
title="An aquarium hobbyist poisoning: Identification of new palytoxins in Palythoa cf. toxica and complete detoxification of the aquarium water by activated carbon",
journal="Toxicon: Journal of the International Society on Toxinology",
year="2016",
author="Tartaglione, Luciana and Pelin, Marco and Morpurgo, Massimo and Dell'Aversano, Carmela and Montenegro, Javier and Sacco, Giuseppe and Sosa, Silvio and Reimer, James Davis and Ciminiello, Patrizia and Tubaro, Aurelia",
volume="121",
number="",
pages="41-50",
abstract="Palytoxin (PLTX) is a lethal natural toxin often found in Palythoa zoantharians that, together with its congeners, may induce adverse effects in humans after inhalation of toxic aerosols both in open-air and domestic environments, namely in the vicinity of public and private aquaria. In this study, we describe a poisoning of an aquarium hobbyist who was hospitalized after handling a PLTXs-containing zoantharian hexacoral. Furthermore, we provide evidence for water detoxification. The zoantharian was morphologically and genetically identified as Palythoa cf. toxica (Cnidaria: Anthozoa). Palytoxin itself and two new PLTX congeners, a hydroxyPLTX and a deoxyPLTX, were detected and structurally identified by liquid chromatography high resolution multiple stage mass spectrometry (LC-HRMS(n), n = 1, 2). Total and individual toxins were quantified by LC-HRMS and sandwich ELISA both in the zoantharian (93.4 and 96.80 μg/g, respectively) and in the transport water (48.3 and 42.56 μg/mL, respectively), with an excellent mean bias of 1.3% between the techniques. Activated carbon adsorbed 99.7% of PLTXs contained in the seawater and this represents a good strategy for preventing aquarium hobbyist poisonings.<br><br>Copyright © 2016. Published by Elsevier Ltd.<p /> <p>Language: en</p>",
language="en",
issn="0041-0101",
doi="10.1016/j.toxicon.2016.08.012",
url="http://dx.doi.org/10.1016/j.toxicon.2016.08.012"
}