@article{ref1,
title="Epidemiology of comorbid conditions among adults 50 years and older with traumatic brain injury",
journal="Journal of head trauma rehabilitation",
year="2018",
author="Kumar, Raj G. and Juengst, Shannon B. and Wang, Zhensheng and Dams-Oʼconnor, Kristen and Dikmen, Sureyya S. and Oʼneil-Pirozzi, Therese M. and Dahdah, Marie N. and Hammond, Flora M. and Felix, Elizabeth R. and Arenth, Patricia M. and Wagner, Amy K.",
volume="33",
number="1",
pages="15-24",
abstract="OBJECTIVES: Aging individuals with traumatic brain injury (TBI) experience multiple comorbidities that can affect recovery from injury. The objective of this study was to describe the most commonly co-occurring comorbid conditions among adults 50 years and older with TBI. SETTING: Level I Trauma centers. PARTICIPANTS: Adults 50 years and older with moderate/severe TBI enrolled in the TBI-Model Systems (TBI-MS) from 2007 to 2014 (n = 2134). <br><br>DESIGN: A TBI-MS prospective cohort study. MAIN MEASURES: International Classification of Disease-9th Revision codes collapsed into 45 comorbidity categories. Comorbidity prevalence estimates and trend analyses were conducted by age strata (50-54, 55-64, 65-74, 75-84, ≥85 years). A dimension reduction method, Treelet Transform, classified clusters of comorbidities that tended to co-occur. <br><br>RESULTS: The 3 most commonly occurring comorbid categories were hypertensive disease (52.6/100 persons), other diseases of the respiratory system (51.8/100 persons), and fluid component imbalances (43.7/100 persons). Treelet Transform classified 3 clusters of comorbid codes, broadly classified as (1) acute medical diseases/infections, (2) chronic conditions, and (3) substance abuse disorders. <br><br>CONCLUSION: This study provides valuable insight into comorbid conditions that co-occur among adults 50 years and older with TBI and provides a foundation for future studies to explore how specific comorbidities affect TBI recovery.<p /> <p>Language: en</p>",
language="en",
issn="0885-9701",
doi="10.1097/HTR.0000000000000273",
url="http://dx.doi.org/10.1097/HTR.0000000000000273"
}