@article{ref1,
title="Increased risk of suicide in schizophrenia patients with linkage to chromosome 13q",
journal="Psychiatry research",
year="2017",
author="Malherbe, P. J. and Karayiorgou, M. and Ehlers, R. and Roos, Johannes L.",
volume="251",
number="",
pages="34-35",
abstract="We link schizophrenia in families from the genetically isolated South African Afrikaner population to chromosome 13q (n =51), 1p (n =23) and combined 13q & 1p (n =18). Patients with linkages to chromosome 13q were 4.16 times more likely to meet diagnostic criteria for schizoaffective disorder compared to patients with linkage to 1p. A third of patients with linkage to both 13q &1p met diagnostic criteria for SAD. There was a significant positive relationship between suicidality and a diagnosis of schizoaffective disorder. Identifying linkage to chromosome 13q may be informative in identifying suicide risk early and prevent morbidity and mortality in schizophrenia patients.<br><br>Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="0165-1781",
doi="10.1016/j.psychres.2017.02.008",
url="http://dx.doi.org/10.1016/j.psychres.2017.02.008"
}