@article{ref1,
title="IMPACT score for traumatic brain injury: validation of the prognostic tool in a Spanish cohort",
journal="Journal of head trauma rehabilitation",
year="2018",
author="Egea-Guerrero, Juan José and Rodríguez-Rodríguez, Ana and Gordillo-Escobar, Elena and Fernández-Delgado, Esperanza and Martínez-Roldán, Ángela and Roldán-Reina, Álvaro and Durán-Martínez, Pilar and de Vega-Ríos, Enrique and Freire-Aragón, María Dolores and Vilches-Arenas, Angel and Murillo-Cabezas, Francisco and Quintana-Díaz, Manuel",
volume="33",
number="1",
pages="46-52",
abstract="BACKGROUND: The aim of this work was to validate the IMPACT (International Mission for Prognosis and Analysis of Clinical Trials in TBI) model in a Spanish cohort of patients with moderate-severe TBI (traumatic brain injury). SETTING: Two level I neurotrauma centers. PARTICIPANTS: Patients admitted to these hospitals between 2011 and 2014 with a diagnosis of TBI and a Glasgow Coma Scale score of 12 or less. <br><br>DESIGN: Prospective observational study. MAIN MEASURES: We collected prospectively the clinical variables included in the IMPACT models. Outcome evaluation was prospectively done at 6-month follow-up according to the Glasgow Outcome Scale. <br><br>RESULTS: A total of 290 patients were included in the study. Forty-seven patients (16.2%) died within 6 months post-TBI, and 74 patients (25.5%) had an unfavorable outcome. The Hosmer-Lemeshow test revealed that there was no difference between observed and predicted outcomes; hence, the 3 models displayed adequate calibration for predicting 6-month mortality or unfavorable outcome. The receiver operating characteristic curve indicated that the 3 models (Core, Extended, and Lab) could accurately discriminate between favorable and unfavorable outcomes, as well as between survival and mortality (P <.001). <br><br>CONCLUSION: The IMPACT model validates prediction of 6-month outcomes in a Spanish population of moderate-severe TBI. IMPACT Lab model is the one that presents a higher discriminative capacity. These results encourage the implementation of the IMPACT model as a prognostic tool in the management of patients with TBI.<p /> <p>Language: en</p>",
language="en",
issn="0885-9701",
doi="10.1097/HTR.0000000000000292",
url="http://dx.doi.org/10.1097/HTR.0000000000000292"
}