@article{ref1,
title="Toxicity of the venom of Latrodectus (Araneae: Theridiidae) spiders from different regions of Argentina and neutralization by therapeutic antivenoms",
journal="Toxicon: Journal of the International Society on Toxinology",
year="2017",
author="de Roodt, Adolfo Rafael and Lanari, Laura Cecilia and Laskowicz, Rodrigo Daniel and Costa de Oliveira, Vanessa and Irazu, Lucia Elvira and González, Alda and Giambelluca, Luis and Nicolai, Néstor and Barragán, Javier Hugo and Ramallo, Leticia and López, Raúl Alfredo and Lopardo, Jorge and Jensen, Oscar and Larrieu, Edmundo and Calabró, Arnoldo and Vurcharchuc, Miriam Guadalupe and Lago, Néstor Rubén and García, Susana Isabel and de Titto, Ernesto Horacio and Damín, Carlos Fabián",
volume="130",
number="",
pages="63-72",
abstract=""Black widow" spiders belong to the genus Latrodectus and are one of the few spiders in the world whose bite can cause severe envenomation in humans and domestic animals. In Argentina, these spiders are distributed throughout the country and are responsible for the highest number of bites by spiders of toxicological sanitary interest. Here, we studied the toxicity and some biochemical and immunochemical characteristics of eighteen venom samples from Latrodectus spiders from eight different provinces of Argentina, and the neutralization of some of these samples by two therapeutic antivenoms used in the country for the treatment of envenomation and by a anti-Latrodectus antivenom prepared against the venom of Latrodectus mactans from Mexico. We observed important toxicity in all the samples studied and a variation in the toxicity of samples, even in those from the same region and province and even in the same Latrodectus species from the same region. The therapeutic antivenoms efficiently neutralized all the venoms studied.
Copyright © 2017 Elsevier Ltd. All rights reserved. Language: en
",
language="en",
issn="0041-0101",
doi="10.1016/j.toxicon.2017.02.029",
url="http://dx.doi.org/10.1016/j.toxicon.2017.02.029"
}