@article{ref1,
title="Early Huntington's disease: impulse control deficits but correct judgment regarding risky situations",
journal="Journal of Huntington's disease",
year="2017",
author="Galvez, Victor and Fernandez-Ruiz, Juan and Bayliss, Leo and Ochoa-Morales, Adriana and Hernandez-Castillo, Carlos R. and Diaz, Rosalinda and Campos-Romo, Aurelio",
volume="6",
number="1",
pages="73-78",
abstract="BACKGROUND: Huntington's disease (HD) patients show alterations in decision making tasks. However, it is still uncertain if these deficits are due to poor judgment regarding risky situations, or to impulse control deficits. <br><br>OBJECTIVE: To elucidate whether decision-making in patients is related to genuine risk behavior or to impulse control deficits. <br><br>METHODS: To test between these two alternative possibilities, we evaluated the performance of 19 prodromal HD patients and 19 matched healthy controls in the Cambridge Gambling Task (CGT). This task assesses decision-making while dissociating between genuine risk-taking behaviors (ascending condition) from impulsive behavior (descending condition). <br><br>RESULTS: The results showed that patients and controls had the same performance during all trials in the ascending condition, reflecting a correct judgment regarding risky situations; however, during the descending condition, patients responded before the controls in all trials, making a significantly larger number of higher bets. Unlike the control group, they did not wait for more optimal subsequent options. <br><br>CONCLUSION: These results suggest impulse control deficits in HD gene carriers, but unimpaired risk-taking judgment.<p /> <p>Language: en</p>",
language="en",
issn="1879-6397",
doi="10.3233/JHD-160223",
url="http://dx.doi.org/10.3233/JHD-160223"
}