@article{ref1,
title="Outcome after operative intervention for traumatic brain injuries in the elderly",
journal="Asian journal of neurosurgery",
year="2017",
author="Li, Lai-Fung and Lui, Wai-Man and Wong, Heidi Hay-Tai and Yuen, Wai-Kei and Leung, Gilberto Ka-Kit",
volume="12",
number="1",
pages="37-43",
abstract="INTRODUCTION: The management of traumatic brain injuries in the elderly (age ≥ 65 years) is a constant dilemma. The aim of this study is to investigate for factors that may predict outcome of operative treatment in this group of patients. <br><br>MATERIALS AND METHODS: A retrospective analysis was conducted on 68 elderly patients who had been operated in a designated center from 2006 to 2010. Patients' age, Glasgow Coma score (GCS), pupillary responses, imaging findings, medical conditions, and the use of anticoagulant/antiplatelet agents on patient outcomes were studied. <br><br>RESULTS: The overall mortality rate was 55.9%. Older age, abnormal pupillary response, low GCS, the presence of midline shift and cistern obliteration on computerized tomography were associated with poor survival. Patient aged 75-84 with normal bilateral pupillary response still had an overall survival rate of 52.6% and good outcomes (Glasgow outcome score: 4 or 5) in 36.8% of patients. Abnormal pupillary response in at least one eye and preoperative GCS ≤ 12 were associated with very poor prognosis. <br><br>CONCLUSIONS: More advanced age was found to be associated with progressively worse outcome. A subgroup patients aged below 85 would survive and could achieve good clinical outcome. The prognosis of those aged over 85 with moderate or severe head injuries was extremely poor.<p /> <p>Language: en</p>",
language="en",
issn="1793-5482",
doi="10.4103/1793-5482.148787",
url="http://dx.doi.org/10.4103/1793-5482.148787"
}