
@article{ref1,
title="Post-traumatic seizures in a rural Nigerian neurosurgical service",
journal="World neurosurgery",
year="2017",
author="Rabiu, T. B. and Adetunmbi, B.",
volume="104",
number="",
pages="367-371",
abstract="BACKGROUND: Traumatic brain injury (TBI) is a recognized risk factor for seizures. In Nigeria, there is paucity of literature on post-traumatic seizures (PTS). This study provides the profile and pattern of PTS in TBI patients in a rural Nigerian neurosurgical service. <br><br>METHOD: A prospective observational study of TBI patients was done. Clinical and radiological data including outcomes of care were analysed with SPSS version 15. A p-value of <0.05 was considered statistically significant. <br><br>RESULT: 199 patients were managed for TBI. There were 20(10.1%) cases of PTS. Mean age was 28.4years (range: 5-80years) and most were males {16(80.0%)}. The average admission GCS was 10 (range: 3-15). Of the 20 PTS patients, 10(50.0%) had mild head injury while 3(15.0%) and 7(35.0%) had moderate and severe head injuries respectively. PTS peaked in young patients aged 17-45 years (14, 70%). Fourteen (14, 70.0%) had immediate PTS, while 6(30.0%) had early PTS. Increasing severity of head injury resulted in higher incidence of PTS (7.8%, 10.3% and 17.1% for mild, moderate and severe head injuries respectively). <br><br>FINDINGS of ASDH and contusions on CT scan are significant risk factors for PTS (Chi-square: 22.8; p-value: 0.0004). Five (25.0%) patients required anticonvulsant therapy because of seizure recurrence but only one progressed to late PTS. Four (20.0%) died while the rest had good outcome. <br><br>CONCLUSION: Severe TBI and CT findings of acute subdural haematoma and cerebral contusions are predictors of PTS in our environment. Progression of immediate/early to late PTS is rare.<br><br>Copyright © 2017 Elsevier Inc. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="1878-8750",
doi="10.1016/j.wneu.2017.04.133",
url="http://dx.doi.org/10.1016/j.wneu.2017.04.133"
}