@article{ref1,
title="Traumatic brain injury research and expression of caveolin-1 and its relationship with disease prognosis",
journal="Pakistan journal of pharmaceutical sciences",
year="2017",
author="Wang, Xiangdong and Ren, Xinliang and Wang, Yanhong and Li, Jianhong and Guo, Tiezhu and Li, Fan and Zhao, Zhiqiang",
volume="30",
number="3",
pages="997-1000",
abstract="The objective of this paper is to study the expression of caveolin-1 in the traumatic brain injury patients and its relationship with disease prognosis. Caveolin-1 was measured in 52 patients with ventricular hemorrhage within 8h, 24h, 48h, 72h and 1 week after onset by enzyme-linked immunosorbent assay (ELISA), to observe the changes of cerebrospinal fluid caveolin-1. The level of caveolin-1 in the brain of all patients was higher than that of the control group at 8 h, 24h, 48 h, 72h and 1 weeks after the onset (P<0.05) and the level of caveolin-1 in cerebrospinal fluid (CSF) of the severe group was higher than that of the light-medium group within 8h, 24h, 48 h and 72h after the onset (P<0.05). The level of caveolin-1 in CSF was significantly increased in patients with ventricular hemorrhage within 8h, 24h, 48h, 72h and 1 weeks after onset, and the expression of caveolin-1 in brain was related to the severity of craniocerebral injury. Therefore, the expression of caveolin-1 can be used as an indicator of the prognosis of traumatic brain injury disease.<p /> <p>Language: en</p>",
language="en",
issn="1011-601X",
doi="",
url="http://dx.doi.org/"
}