@article{ref1,
title="Interaction between the ADH1B*3 allele and drinking motives on alcohol use among Black college students",
journal="American journal of drug and alcohol abuse encompassing all addictive disorders",
year="2018",
author="Park, Aesoon and Belote, John M. and Suryadevara, Kavita and Kim, Jueun and Desalu, Jessica M. and Zaso, Michelle J.",
volume="44",
number="3",
pages="329-338",
abstract="BACKGROUND: Black young adults have lower rates of alcohol use than other racial groups. Genetic factors may protect against drinking. Specifically, the ADH1B*3 allele is present almost exclusively in Black populations and has been protective against alcohol use and alcohol use disorder. The protective effects of the ADH1B*3 allele, however, may differ as a function of alcohol-promoting cognitions. <br><br>OBJECTIVES: The current study examined whether ADH1B*3 moderated relations of drinking motives with alcohol consumption among Black college drinkers. <br><br>METHODS: Participants were 241 undergraduate students of self-identified Black race (mean age = 20 years; 66% female) who reported consuming alcohol at least once in the past 30 days. <br><br>RESULTS: ADH1B*3 was not significantly associated with drinking motives or drinking behaviors. However, significant, albeit small, interaction effects of ADH1B*3 with drinking motives on drinking behavior were found; the presence of an ADH1B*3 allele protected against greater drinking quantity among students with high social motives (incidence rate ratio [IRR] = 0.95, 95% CI [0.92, 0.99]) and against frequent drinking among students with low coping motives (IRR = 1.06, 95% CI [1.01, 1.11]). <br><br>CONCLUSION: These findings represent a novel demonstration of genetic modulation of alcohol-related cognitions within Black college drinkers, although replication is needed. <br><br>RESULTS represent an initial step toward better characterizing individual differences in associations of drinking motives with drinking behavior, with potential implications for interventions aimed at motivational processes in alcohol use.<p /> <p>Language: en</p>",
language="en",
issn="0095-2990",
doi="10.1080/00952990.2017.1339054",
url="http://dx.doi.org/10.1080/00952990.2017.1339054"
}