@article{ref1,
title="The mediator effect of personality traits on the relationship between childhood abuse and depressive symptoms in schizophrenia",
journal="Psychiatry research",
year="2017",
author="Okubo, Ryo and Inoue, Takeshi and Hashimoto, Naoki and Suzukawa, Akio and Tanabe, Hajime and Oka, Matsuhiko and Narita, Hisashi and Ito, Koki and Kako, Yuki and Kusumi, Ichiro",
volume="257",
number="",
pages="126-131",
abstract="Previous studies indicated that personality traits have a mediator effect on the relationship between childhood abuse and depressive symptoms in major depressive disorder and nonclinical general adult subjects. In the present study, we aimed to test the hypothesis that personality traits mediate the relationship between childhood abuse and depressive symptoms in schizophrenia. We used the following questionnaires to evaluate 255 outpatients with schizophrenia: the Child Abuse and Trauma Scale, temperament and character inventory, and Patients Health Questionnire-9. Univariate analysis, multiple regression analysis, and structured equation modeling (SEM) were used to analyze the data. The relationship between neglect and sexual abuse and the severity of depressive symptoms was mostly mediated by the personality traits of high harm avoidance, low self-directedness, and low cooperativeness. This finding was supported by the results of stepwise multiple regression analysis and the acceptable fit indices of SEM. Thus, our results suggest that personality traits mediate the relationship between childhood abuse and depressive symptoms in schizophrenia. The present study and our previous studies also suggest that this mediator effect could occur independent of the presence or type of mental disorder. Clinicians should routinely assess childhood abuse history, personality traits, and their effects in schizophrenia.<br><br>Copyright © 2017. Published by Elsevier B.V.<p /> <p>Language: en</p>",
language="en",
issn="0165-1781",
doi="10.1016/j.psychres.2017.06.039",
url="http://dx.doi.org/10.1016/j.psychres.2017.06.039"
}