@article{ref1,
title="Fatigue following traumatic brain injury in children and adolescents: a longitudinal follow-up 6 to 12 months after injury",
journal="Journal of head trauma rehabilitation",
year="2018",
author="Crichton, Alison and Anderson, Vicki and Oakley, Ed and Greenham, Mardee and Hearps, Stephen and Delzoppo, Carmel and Beauchamp, Miriam H. and Hutchison, James S. and Guerguerian, Anne-Marie and Boutis, Kathy and Babl, Franz E.",
volume="33",
number="3",
pages="200-209",
abstract="BACKGROUND: Longitudinal fatigue data in children suffering from traumatic brain injury (TBI) are lacking. <br><br>OBJECTIVES: To examine the effects of time postinjury (6-12 months) and injury severity on fatigue after childhood TBI. Secondarily, we compared fatigue 12 months postinjury against published control data. SETTING: Three tertiary children's hospitals across Australia (n = 1) and Canada (n = 2). PARTICIPANTS: Parents (n = 109) of children (mean [M] = 9.9 years at injury; range, 1.0-16.9 years) admitted to one of 3 participating hospitals with mild (n = 69) or moderate/severe (n = 37) TBI. <br><br>DESIGN: Longitudinal prospective study. MEASURES: Primary: Pediatric Quality of Life Multidimensional Fatigue Scale (total, general, sleep/rest, and cognitive), rated by parents 6 and 12 months postinjury. Secondary: Pediatric Injury Functional Outcome Scale (fatigue and sleep items, rated on recruitment and 6 and 12 months postinjury). Demographic and children data were collected at recruitment. <br><br>RESULTS: Mixed-models analysis demonstrated nonsignificant effects of time (6 vs 12 months postinjury) on multidimensional fatigue scores. Cognitive fatigue worsened over time. Moderate/severe TBI was associated with worse fatigue 12 months postinjury (general, P =.03; cognitive, P =.02). Across all severities, fatigue 12 months postinjury was significantly worse compared with control data (total fatigue, P <.001; all domains, all Ps <.025). <br><br>CONCLUSION: Fatigue remains significant at 12 months since injury, particularly for those with moderate/severe TBI.<p /> <p>Language: en</p>",
language="en",
issn="0885-9701",
doi="10.1097/HTR.0000000000000330",
url="http://dx.doi.org/10.1097/HTR.0000000000000330"
}