@article{ref1,
title="Gray matter abnormalities in the inhibitory circuitry of young binge drinkers: a voxel-based morphometry study",
journal="Frontiers in psychology",
year="2017",
author="Sousa, Sónia S. and Sampaio, Adriana and Marques, Paulo and Gonçalves, Óscar F. and Crego, Alberto",
volume="8",
number="",
pages="e1567-e1567",
abstract="Binge drinking (BD) is defined as a pattern of high alcohol intake in a short time followed by periods of abstinence. This behavior is very common in adolescence, a developmental stage characterized by the maturation of the prefrontal and striatal networks, important circuits underlying the capacity to control and regulate the behavior. In this study, we conducted a voxel-based morphometry (VBM) analysis, using a region of interest (ROI) analysis of brain regions associated with inhibitory control and self-regulatory processes, in a group of 36 young college students, 20 binge drinkers (BDs) and 16 alcohol abstinent controls (AAC). <br><br>RESULTS showed increased gray matter (GM) densities in the left middle frontal gyrus in BDs, when compared with alcohol abstinent controls. Additionally, a ROI-based Pearson analysis documented positive correlations between the left middle frontal gyrus GM densities and the self-control subscale of the Barratt Impulsiveness Scale (BIS), in the BD group. These findings highlight abnormalities in core brain regions associated with self-regulatory processes in the BD group.<p /> <p>Language: en</p>",
language="en",
issn="1664-1078",
doi="10.3389/fpsyg.2017.01567",
url="http://dx.doi.org/10.3389/fpsyg.2017.01567"
}