@article{ref1,
title="Is fear of falling associated with decline in global cognitive functioning in older adults: findings from the Irish Longitudinal Study on Ageing",
journal="Journal of the American Medical Directors Association",
year="2018",
author="Peeters, Geeske and Leahy, Siobhan and Kennelly, Sean and Kenny, Rose Anne",
volume="19",
number="3",
pages="248-254.e3",
abstract="BACKGROUND: Fear of falling (FoF) is present in 20% to 85% of older adults and may be an early marker of decline in global cognitive functioning (GCF). We tested the hypothesis that FoF is associated with lower levels of GCF (cross-sectional) and greater decline in GCF (prospective) in adults aged 50 and older. <br><br>DESIGN: Observational cohort study. SETTING: The Irish Longitudinal Study on Ageing, a population-based study. PARTICIPANTS: Data were from 4931 participants (mean age 62.9 ± 9.1, range 50-98, 54.3% female). MEASUREMENTS: FoF was based on self-report in 2010. GCF was measured with the Montreal Cognitive Assessment (MoCA) and Mini Mental Status Examination (MMSE) in 2010 and 2014. The cross-sectional association was examined using linear regression unadjusted and after adjustment for demographic and health factors. The prospective association between FoF and the odds of >1-SD decline in GCF were examined using logistic regression. Interaction with age and mediation by social and physical activities were examined. <br><br>RESULTS: In 2010, 21.9% of participants reported FoF. In the unadjusted cross-sectional models, those with FoF had lower scores on the MoCA (B -1.15, 95% confidence interval [CI] -1.40 to -0.90) and MMSE (B -0.52, CI -0.67 to -0.37). In the unadjusted prospective models, FoF was associated with a greater odds of decline in MoCA (odds ratio [OR] 1.60, CI 1.26-2.04) and MMSE (OR 1.64, CI 1.29-2.08). After adjustment for covariates, all associations attenuated and were no longer statistically significant, except the association with decline in MoCA (OR 1.32, CI 1.01-1.71). No statistically significant interaction with age was found (P > .37). Additional adjustment for social and physical activity did not change the results. <br><br>CONCLUSIONS: The findings provide weak evidence for FoF as a predictor of cognitive decline.<br><br>Copyright © 2017 AMDA − The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="1525-8610",
doi="10.1016/j.jamda.2017.09.012",
url="http://dx.doi.org/10.1016/j.jamda.2017.09.012"
}