
@article{ref1,
title="Falls in older adults with multiple myeloma",
journal="European journal of haematology",
year="2018",
author="Wildes, Tanya M. and Fiala, Mark A.",
volume="100",
number="3",
pages="273-278",
abstract="OBJECTIVE: To examine the prevalence of falls, factors associated with falls and the relationship between falls and survival in older adults with multiple myeloma METHODS: In an analysis of the Surveillance, Epidemiology and End Results (SEER)-Medicare Health Outcomes Survey (MHOS) linked database, we examined 405 older adults with MM and 513 matched non-cancer controls. The primary outcome was self-reported within the past 12 months. Age, race, gender, symptoms and comorbidities were self-reported in the MHOS. Survival was calculated from SEER data RESULTS: Of the patients with MM, 171 were within 1 year of diagnosis (cohort 1) and 234 were ≥1 year post-diagnosis (cohort 2). Patients in cohort 1 and 2 were more likely to have fallen than controls (26% and 33% vs 23%, p=0.012). On multivariate analysis, among patients with myeloma (combined cohorts 1&2), factors associated with falls included self-report of fatigue [aOR 2.52 (95% CI 1.34-4.93)], depression [aOR 1.90 (95% CI 1.14-3.18)], or poorer general health [aOR 1.86 (95% CI 1.05-3.36)]. Falls were not associated with survival CONCLUSIONS: Older adults with MM have a greater prevalence of falls than matched controls. Self- reported fatigue, depression and poorer general health are associated with greater odds of falls. This article is protected by copyright. All rights reserved.<br><br>This article is protected by copyright. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="0902-4441",
doi="10.1111/ejh.13009",
url="http://dx.doi.org/10.1111/ejh.13009"
}