@article{ref1,
title="Factors influencing psychological well-being in patients with Parkinson's disease",
journal="PLoS one",
year="2017",
author="Nicoletti, Alessandra and Mostile, Giovanni and Stocchi, Fabrizio and Abbruzzese, Giovanni and Ceravolo, Roberto and Cortelli, Pietro and D'Amelio, Marco and De Pandis, Maria F. and Fabbrini, Giovanni and Pacchetti, Claudio and Pezzoli, Gianni and Tessitore, Alessandro and Canesi, Margherita and Zappia, Mario",
volume="12",
number="12",
pages="e0189682-e0189682",
abstract="BACKGROUND: Both motor and non-motor symptoms could contribute to significant deterioration of psychological well-being in patients with Parkinson's disease (PD). However, its assessment has been only indirectly evaluated using tools based on health-related quality of life (HRQoL), such as the PDQ-39 scale. <br><br>OBJECTIVES: To evaluate psychological well-being in PD using a specific tool of assessment, the Psychological Well-being Scale (PWS), and its clinical correlates. <br><br>METHODS: This article reports data of patients' perception of health state, as measured by means of the PWS, from an epidemiological, cross-sectional study conducted in Italian PD patients (FORTE Study). We tested possible relationship between well-being and clinical characteristics including fatigue, depression, sleep disruption and HRQoL. <br><br>RESULTS: 272 patients completed the PWS questionnaire. Significant and clinically-relevant correlations were found between PWS total score and Parkinson's Fatigue Scale, Beck Depression Inventory, UPDRS Section I, PD Sleep Scale and PDQ-39 for HRQoL scores. Only clinically negligible correlations were found between PWS and motor scores. <br><br>CONCLUSIONS: Non-motor symptoms have a significant impact on psychological well-being in PD patients.<p /> <p>Language: en</p>",
language="en",
issn="1932-6203",
doi="10.1371/journal.pone.0189682",
url="http://dx.doi.org/10.1371/journal.pone.0189682"
}