@article{ref1,
title="Risk of erectile dysfunction after traumatic brain injury: a nationwide population-based cohort study in Taiwan",
journal="American journal of men's health",
year="2018",
author="Yang, Yun-Ju and Chien, Wu-Chien and Chung, Chi-Hsiang and Hong, Kun-Ting and Yu, Yi-Lin and Hueng, Dueng-Yuan and Chen, Yuan-Hao and Ma, Hsin-I and Chang, Hsin-An and Kao, Yu-Chen and Yeh, Hui-Wen and Tzeng, Nian-Sheng",
volume="12",
number="4",
pages="913-925",
abstract="INTRODUCTION: In our study, we aimed to investigate the association between a traumatic brain injury (TBI) and subsequent erectile dysfunction (ED). This is a population-based study using the claims dataset from The National Health Insurance Research Database. <br><br>METHODS: We included 72,642 patients with TBI aged over 20 years, retrospectively, selected from the longitudinal health insurance database during 2000-2010, according to the ICD-9-CM. The control group consisted of 217,872 patients without TBI that were randomly chosen from the database at a ratio of 1:3, with age- and index year matched. Cox proportional hazards analysis was used to estimate the association between the TBI and subsequent ED. <br><br>RESULTS: After a 10-year follow-up, the incidence rate of ED was higher in the TBI patients when compared with the non-TBI control group (24.66 and 19.07 per 100,000, respectively). Patients with TBI had a higher risk of developing ED than the non-TBI cohort after the adjustment of the confounding factors, such as age, comorbidity, residence of urbanization and locations, seasons, level of care, and insured premiums (adjusted hazard ratio (HR) = 2.569, 95% CI [1.890, 3.492], p <.001). <br><br>CONCLUSION: This is the first study using a comprehensive nationwide database to analyze the association of ED and TBI in the Asian population. After adjusted the confounding factors, patients with TBI have a significantly higher risk of developing ED, especially organic ED, than the general population. This finding might remind clinicians that it's crucial in early identification and treatment of ED in post-TBI patients.<p /> <p>Language: en</p>",
language="en",
issn="1557-9883",
doi="10.1177/1557988317750970",
url="http://dx.doi.org/10.1177/1557988317750970"
}