@article{ref1,
title="Biological alterations affecting risk of adult psychopathology following childhood trauma: a review of sex differences",
journal="Clinical psychology review",
year="2018",
author="Tiwari, Ashwini and Gonzalez, Andrea",
volume="66",
number="",
pages="69-79",
abstract="Childhood trauma exposure is a significant public health problem. While adult mental health consequences of such experiences are well documented, sex differences in both prevalence and severity are less understood. Sex-based differences in biological circuitry and physiological trauma responses are proposed to potentiate the differential risk for pathogenesis of mental health disorders among adults. This paper will provide a contextualized summary of neuroendocrine, neuroimaging, and behavioral epigenetic studies on biological sex differences contributing to internalizing psychopathology, specifically posttraumatic stress disorder and depression, among adults with a history of childhood abuse. This review concludes with a discussion of implications for trauma interventions and sex-based biopsychological research in violence prevention.<br><br>Copyright © 2018 Elsevier Ltd. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="0272-7358",
doi="10.1016/j.cpr.2018.01.006",
url="http://dx.doi.org/10.1016/j.cpr.2018.01.006"
}