@article{ref1,
title="The impact of vitamin D supplementation on attention-deficit hyperactivity disorder in children",
journal="Annals of pharmacotherapy",
year="2018",
author="Elshorbagy, Hatem Hamed and Barseem, Naglaa Fathy and Abdelghani, Waleed Elsayed and Suliman, Hany Abdelaziz Ibrahim and Al-Shokary, Ashraf Hamed and Abdulsamea, Sameh Elsayed and Elsadek, Akram Elshafey and Abdel Maksoud, Yehia Hamed and Nour El Din, Dalia Mohamed Abd El-Hassib",
volume="52",
number="7",
pages="623-631",
abstract="BACKGROUND: The role of nutrients and dietary factors in attention-deficit hyperactivity disorder (ADHD) remains unclear. <br><br>OBJECTIVES: The primary objective was to evaluate the serum vitamin D level in children with a diagnosis of ADHD. The secondary objective was to detect the effect of vitamin D supplementation on cognitive function in those with vitamin D deficiency. <br><br>METHODS: A total of 50 children with ADHD and 40 healthy controls were included in the study. We measured the serum level of vitamin D. Patients with vitamin D deficiency were subdivided into 2 groups: one with vitamin D supplementation and the other without vitamin D supplementation. Further assessment and follow-up of children with ADHD was done. The Wisconsin Card Sorting Test, Conners' Parent Rating Scale, and Wechsler Intelligence Scale for Children were performed at baseline and follow-up in all cohorts with an ADHD diagnosis. <br><br>RESULTS: The diagnosis of vitamin D deficiency was significantly greater in children with ADHD compared with the control group ( P < 0.05). Children with ADHD had significantly ( P = 0.0009) lower values of serum vitamin D (17.23 ± 8.98) than the control group(31.47 ± 14.42). The group receiving vitamin D supplementation demonstrated improvement in cognitive function in the conceptual level, inattention, opposition, hyperactivity, and impulsivity domains. <br><br>CONCLUSION: Vitamin D supplementation in children with ADHD may improve cognitive function.<p /> <p>Language: en</p>",
language="en",
issn="1060-0280",
doi="10.1177/1060028018759471",
url="http://dx.doi.org/10.1177/1060028018759471"
}