@article{ref1,
title="Attempted suicide by Flécainide overdose: a case report",
journal="Tunisie médicale, La",
year="2017",
author="Ben Kilani, Mouna and Naccache, Soufia and Tlili, Rami and Mbarek, Dorra and Longo, Salma and Ben Ameur, Youssef and Boujnah, Mohamed Rachid",
volume="95",
number="6",
pages="451-453",
abstract="Class Ic antiarrythmic overdose is associated with a relatively high mortality. We presenta case report regarding a suicidal intoxication of an 18-year old female with a medical history of Wolff-Parkinson-White syndrome. The preliminary examination highlighted a profound cardiovascular collapse. The electrocardiogram showed a PR interval extended to 360 ms. The QRS complexes were enlarged to 360 ms with a right bundle brunch block appearance associated with left posterior hemibloc. There were repolarization abnormalities such as elevation of the J-point, convex ST segment and biphasic T wave in the right precordial leads (&quot;Brugada-Like ECG pattern&quot;). Sodium bicarbonate was administered. A rapid decrease in the duration of the QRS complexes was noted as well as a slowing of the heart rate. The electrocardiogram aspect on the 4th day showed the reappearance of the ventricular pre-excitation. The severity and lethal potential of Flecainide poisoning are linked to the cardiotoxic effects of these molecules. The prognosis remains poor despite progress in intensive care procedures.<p /> <p>Language: en</p>",
language="en",
issn="0041-4131",
doi="",
url="http://dx.doi.org/"
}