Suicide poisoning corresponds to 4.9-23.2% of the poisonings treated in pediatric emergency services in Europe1. Multiple drugs are often involved and often unknown. The attention of these patients is based on the stabilization, monitoring and application of support measures, being fundamental the search for guiding signs that orient towards the causal agents and allow to foresee the potential toxicity. Lactic metabolic acidosis usually appears in severe patients, as a marker of tissue hypoxia, and has been shown to be an independent risk factor for mortality. In intoxicated patients, hyperlactacidemia is also associated with a worse prognosis, although in most cases it is due to a direct toxicological mechanism and can occur in clinically stable patients, being an early marker of toxicity. The management of lactic acidosis in the context of an intoxication differs from the management in the serious non-intoxicated patient. In the latter treatment is based on respiratory and hemodynamic stabilization, while in the intoxicated it may be necessary to use extrarenal clearance techniques.
Language: es
", language="es", issn="1695-4033", doi="10.1016/j.anpedi.2018.02.024", url="http://dx.doi.org/10.1016/j.anpedi.2018.02.024" }