@article{ref1,
title="Interoception in anxiety and depression",
journal="Brain structure and function",
year="2010",
author="Paulus, Martin P. and Stein, Murray B.",
volume="214",
number="5-6",
pages="451-463",
abstract="We review the literature on interoception as it relates to depression and anxiety, with a focus on belief, and alliesthesia. The connection between increased but noisy afferent interoceptive input, self-referential and belief-based states, and top-down modulation of poorly predictive signals is integrated into a neuroanatomical and processing model for depression and anxiety. The advantage of this conceptualization is the ability to specifically examine the interface between basic interoception, self-referential belief-based states, and enhanced top-down modulation to attenuate poor predictability. We conclude that depression and anxiety are not simply interoceptive disorders but are altered interoceptive states as a consequence of noisily amplified self-referential interoceptive predictive belief states.<p /><p>Language: en</p>",
language="en",
issn="1863-2653",
doi="10.1007/s00429-010-0258-9",
url="http://dx.doi.org/10.1007/s00429-010-0258-9"
}