@article{ref1,
title="Longtime driving induced cerebral hemodynamic elevation and behavior degradation as assessed by fNIRS and a voluntary attention test",
journal="Journal of biophotonics",
year="2018",
author="Li, Ting and Lin, Yu and Gao, Yuan and Zhong, Fulin",
volume="11",
number="12",
pages="e201800160-e201800160",
abstract="Drowsy driving contributes to ~20% of all traffic accidents worldwide. Onsite monitoring the mental condition of a driver and forewarning may be a preventive solution to reduce occurrence of drowsiness and potential accidents. Functional near-infrared spectroscopy (fNIRS) has been successfully utilized in hemodynamics-interpreted functional activity in preliminary voluntary attention experiments. Here, we monitored hemodynamic alternations using fNIRS upon the prefrontal cortex over 13 volunteers in the course of a 7-hour driving simulation and evaluated their reaction capability with a voluntary attention test based on Go/NoGo paradigm. A degradation in attention test score (Accuracy/RT) as well as the elevations in oxy-hemoglobin (Δ[HbO<sub>2</sub> ]) and total hemoglobin (Δ[tHb]) were found significantly correlated with driving duration (Accuracy/RT: r = -0.964, p < 0.001; Δ[HbO<sub>2</sub> ]: r = 0.950, p < 0.001; Δ[tHb]: r = 0.852, p = 0.007). The hemodynamic parameters are in significant inverse correlations with Accuracy/RT (Δ[HbO<sub>2</sub> ]: r = -0.896, p = 0.003; Δ[tHb]: r = -0.844, p = 0.008), indicating the potential to forewarn drivers the attention degradation with onsite fNIRS measurements. This article is protected by copyright. All rights reserved.<br><br>This article is protected by copyright. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="1864-063X",
doi="10.1002/jbio.201800160",
url="http://dx.doi.org/10.1002/jbio.201800160"
}