@article{ref1,
title="Individually-tailored multifactorial intervention to reduce falls in the Malaysian Falls Assessment and Intervention Trial (MyFAIT): a randomized controlled trial",
journal="PLoS one",
year="2018",
author="Tan, Pey June and Khoo, Ee Ming and Chinna, Karuthan and Saedon, Nor I'zzati and Zakaria, Mohd Idzwan and Ahmad Zahedi, Ahmad Zulkarnain and Ramli, Norlina and Khalidin, Nurliza and Mazlan, Mazlina and Chee, Kok Han and Zainal Abidin, Imran and Nalathamby, Nemala and Mat, Sumaiyah and Jaafar, Mohamad Hasif and Khor, Hui Min and Khannas, Norfazilah Mohamad and Majid, Lokman Abdul and Tan, Kit Mun and Chin, Ai-Vyrn and Kamaruzzaman, Shahrul Bahyah and Poi, Philip and Morgan, Karen and Hill, Keith D. and Mackenzie, Lynette and Tan, Maw Pin",
volume="13",
number="8",
pages="e0199219-e0199219",
abstract="OBJECTIVE: To determine the effectiveness of an individually-tailored multifactorial intervention in reducing falls among at risk older adult fallers in a multi-ethnic, middle-income nation in South-East Asia. <br><br>DESIGN: Pragmatic, randomized-controlled trial. SETTING: Emergency room, medical outpatient and primary care clinic in a teaching hospital in Kuala Lumpur, Malaysia. PARTICIPANTS: Individuals aged 65 years and above with two or more falls or one injurious fall in the past 12 months. INTERVENTION: Individually-tailored interventions, included a modified Otago exercise programme, HOMEFAST home hazards modification, visual intervention, cardiovascular intervention, medication review and falls education, was compared against a control group involving conventional treatment. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was any fall recurrence at 12-month follow-up. Secondary outcomes were rate of fall and time to first fall. <br><br>RESULTS: Two hundred and sixty-eight participants (mean age 75.3 ±7.2 SD years, 67% women) were randomized to multifactorial intervention (n = 134) or convention treatment (n = 134). All participants in the intervention group received medication review and falls education, 92 (68%) were prescribed Otago exercises, 86 (64%) visual intervention, 64 (47%) home hazards modification and 51 (38%) cardiovascular intervention. Fall recurrence did not differ between intervention and control groups at 12-months [Risk Ratio, RR = 1.037 (95% CI 0.613-1.753)]. Rate of fall [RR = 1.155 (95% CI 0.846-1.576], time to first fall [Hazard Ratio, HR = 0.948 (95% CI 0.782-1.522)] and mortality rate [RR = 0.896 (95% CI 0.335-2.400)] did not differ between groups. <br><br>CONCLUSION: Individually-tailored multifactorial intervention was ineffective as a strategy to reduce falls. Future research efforts are now required to develop culturally-appropriate and affordable methods of addressing this increasingly prominent public health issue in middle-income nations. TRIAL REGISTRATION: ISRCTN Registry no. ISRCTN11674947.<p /> <p>Language: en</p>",
language="en",
issn="1932-6203",
doi="10.1371/journal.pone.0199219",
url="http://dx.doi.org/10.1371/journal.pone.0199219"
}