@article{ref1,
title="Self-inflicted burn injury is independently associated with increased mortality in a more economically developed country: a propensity score matching analysis",
journal="Journal of burn care and research",
year="2019",
author="Yamamoto, Ryo and Shibusawa, Takayuki and Kurihara, Tomohiro and Sasaki, Junichi",
volume="40",
number="2",
pages="228-234",
abstract="Self-inflicted burn accounts for considerable morbidity and mortality in more economically developed countries, and there is a substantial debate regarding the pathophysiological relevance between self-inflicted burns and unfavorable outcomes. To validate whether self-inflicted injury is an independent predictor of high mortality regardless of the severity of burn, we conducted a retrospective observational study using the Japan Trauma Data Bank, a nationwide database including over 200 major tertiary care centers. Among 2,006 patients with burn who had arrived at collaborating centers between 2004 and 2016, we included patients aged ≥ 15 years, those who did not present with cardiopulmonary arrest upon arrival, and those who had ≥10% total body surface area burns. Patients with missing survival data or unknown mechanism of injury were excluded. In total, 1,094 patients were eligible, of whom 222 (20.3%) had self-inflicted burns. The patients were divided into the self-inflicted and non-self-inflicted groups, and propensity score was calculated using the demographic information of the patients, injury variables, time from injury to hospital arrival, and other survival predictors. Via a propensity score matching, 98 pairs were selected, and the self-inflicted group had a higher mortality than the non-self-inflicted group (43.9% vs. 28.6%, hazard ratio = 1.77; 95% confidence interval = 1.10-2.86; p = 0.02). Inverse probability weighting and multivariate logistic regression were performed as sensitivity analyses, and results validated that self-inflicted burn was independently associated with increased in-hospital mortality. Therefore, patients with self-inflicted burns should receive judicious management, regardless of burn injury severity.<p /> <p>Language: en</p>",
language="en",
issn="1559-047X",
doi="10.1093/jbcr/irz009",
url="http://dx.doi.org/10.1093/jbcr/irz009"
}