
@article{ref1,
title="Effects of the interaction between genetic factors and maltreatment on child and adolescent psychiatric disorders",
journal="Psychiatry research",
year="2019",
author="Carvalho, Carolina Muniz and Pan, Pedro M. and Ota, Vanessa K. and Spindola, Letícia M. and Xavier, Gabriela and Santoro, Marcos L. and Mazzotti, Diego R. and Pellegrino, Renata and Hakonarson, Hakon and Rohde, Luis Augusto Paim and Miguel, Eurípedes Constantino and Gadelha, Ary and Bressan, Rodrigo Affonseca and Belangero, Sintia I.",
volume="273",
number="",
pages="575-577",
abstract="We evaluated the effects of the interaction between child maltreatment (CM) and single nucleotide polymorphisms (SNPs) on development of mental disorders (MD) and psychopathology. We genotyped 720 individuals from a Brazilian community school-based prospective study, focusing on SNPs in 21 genes known to be associated with mental disorders. CM was assessed via a multi-informant-measure, which was previously validated. To test G × CM, we used linear or logistic models depending on variable evaluated (MD or dimensional psychopathology). After Bonferroni multiple comparison correction, we did not find any statistically significant association of G × CM with either MD or psychopathology.<br><br>Copyright © 2019. Published by Elsevier B.V.<p /> <p>Language: en</p>",
language="en",
issn="0165-1781",
doi="10.1016/j.psychres.2019.01.078",
url="http://dx.doi.org/10.1016/j.psychres.2019.01.078"
}