@article{ref1,
title="The persistence of self-injurious and aggressive behavior in males with fragile X syndrome over 8 years: a longitudinal study of prevalence and predictive risk markers",
journal="Journal of autism and developmental disorders",
year="2019",
author="Crawford, Hayley and Karakatsani, Efthalia and Singla, Gursharan and Oliver, Chris",
volume="49",
number="7",
pages="2913-2922",
abstract="Self-injurious and aggressive behaviors are common in fragile X syndrome (FXS). However, little is known about the persistence of these behaviors and associated risk markers. We established the prevalence and persistence of self-injurious and aggressive behaviors over eight years in males with FXS, and associations with risk markers. <br><br>RESULTS showed 77% and 69% persistence rates for self-injurious and aggressive behavior, respectively. Baseline levels of repetitive behavior predicted persistent self-injurious behavior. Chronological age, impulsivity and overactivity were associated with persistent aggressive behavior but only impulsivity predicted persistence. This is the first study to document the persistence of self-injurious and aggressive behavior in FXS over the medium to long term and to identify behavioral risk markers that might facilitate targeted early intervention.<p /> <p>Language: en</p>",
language="en",
issn="0162-3257",
doi="10.1007/s10803-019-04002-3",
url="http://dx.doi.org/10.1007/s10803-019-04002-3"
}