@article{ref1,
title="Lifestyles and the risk of depression in the "Seguimiento Universidad de Navarra" cohort",
journal="European psychiatry",
year="2019",
author="Ruiz-Estigarribia, Liz and Martínez-González, Miguel Angel and Díaz-Gutiérrez, Jesús and Sánchez-Villegas, Almudena and Lahortiga-Ramos, Francisca and Bes-Rastrollo, Maira",
volume="61",
number="",
pages="33-40",
abstract="BACKGROUND: Lifestyles are involved in the pathogenesis of depression and many of these factors can be modified for the potential prevention of depression. Our aim was to assess the association between a healthy-lifestyle score, that includes some less-studied lifestyle indicators, and the risk of depression. <br><br>METHODS: We followed 14,908 participants initially free of any history of depression in the &quot;Seguimiento Universidad de Navarra&quot; (SUN) cohort. Information was collected biennially from 1999 to December 2016. We calculated a healthy-lifestyle score (0-10 points), previously associated with cardioprotection, by giving one point to each of the following components: never smoking, physical activity (> 20 METs-h/week), Mediterranean diet adherence (≥ 4 points), healthy body mass index (≤ 22  kg/m<sup>2</sup>), moderate alcohol consumption (women 0.1-5 g/d; men 0.1-10 g/d of ethanol), avoidance of binge drinking (never more than 5 alcoholic drinks in a row), low television exposure (≤ 2 h/d), short afternoon nap (≤ 30 min/day), time spent with friends (>1 h/d) and working at least 40  h/week. <br><br>RESULTS: During a median follow-up of 10.4 years, we observed 774 new cases of major depression among participants initially free of depression. The highest category (8-10 factors) showed a significant inverse association with a 32% relative risk reduction for depression compared to the lowest category (0-3 factors) (multivariable-adjusted hazard ratio: 0.68; 95% CI:0.49-0.95) (p for trend = 0.010). <br><br>CONCLUSIONS: Adopting a healthy-lifestyle was associated with a lower risk of incident depression in the SUN cohort. This index, including ten simple healthy lifestyle habits, may be useful for a more integrative approach to depression prevention.<br><br>Copyright © 2019 Elsevier Masson SAS. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="0924-9338",
doi="10.1016/j.eurpsy.2019.06.002",
url="http://dx.doi.org/10.1016/j.eurpsy.2019.06.002"
}