@article{ref1,
title="Benzodiazepines and z-drugs - analyses of ambulatory prescriptions from 2006 to 2015",
journal="Psychiatrische Praxis",
year="2019",
author="Verthein, Uwe and Buth, Sven and Holzbach, Rüdiger and Neumann-Runde, Eike and Martens, Marcus-S",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="OBJECTIVE: The majority of medication-dependent persons uses sedatives and hypnotics for many years. In this study we describe trends of benzodiazepine and z-drug prescriptions over a 10-years period. <br><br>METHODS: Prescriptions from 2006 to 2015 (based on German statutory health insurances) from the North German Pharmacy Computing Centre (NARZ) were analysed for the Federal states Schleswig-Holstein, Hamburg, Lower Saxony and Bremen. Data were classified as appropriate (in accordance with the guideline) or inappropriate/risky prescription patterns. <br><br>RESULTS: In a 10-years period 1.64 Million patients received benzodiazepine and/or z-drug prescriptions. Two thirds were women (65.3 %). More than half were 60 years or older. The percentage of patients with appropriate prescriptions (less than 2 months) increased from 51.7 % in 2006 to 60.2 % in 2015. The rate of inappropriate or risky prescription patterns which can be indicative of misuse or dependence dropped from 34.8 % in 2006 to 27.1 % in 2015. <br><br>CONCLUSION: Over the past years the amount of inappropriate or risky benzodiazepine and z-drug prescriptions (which are not in accordance with the guideline) among patients with statutory health insurance is steadily decreasing. However, two fifths of the patients still received prescriptions for long-term intake or in higher doses. It remains unclear to what extent private prescriptions are used for inappropriate or long-term prescriptions of benzodiazepines and z-drugs.<br><br>© Georg Thieme Verlag KG Stuttgart · New York.<p /> <p>Language: de</p> Es wird untersucht, wie sich die kassenärztlichen Verschreibungen von Benzodiazepinen (BZD) und Z-Substanzen (ZS) über einen 10-Jahres-Zeitraum entwickelt haben. GKV-Rezepte des Norddeutschen Apotheken-Rechenzentrums (NARZ) wurden für Schleswig-Holstein, Hamburg, Niedersachsen und Bremen von 2006 - 2015 ausgewertet. 1,64 Mio. Patienten erhielten Verschreibungen von BZD und/oder ZS im 10-Jahres-Zeitraum. 65,3 % sind Frauen, über die Hälfte sind 60 Jahre oder älter. Der Anteil an Patienten mit leitliniengerechten Verschreibungen steigt von 51,7 % in 2006 auf 60,2 % in 2015. Problematische Verschreibungen gehen von 34,8 % auf 27,1 % zurück. Der Anteil leitlinienabweichender Verschreibungen von BZD und ZS, die auf Missbrauch oder Abhängigkeit deuten, ist unter GKV-Patienten seit vielen Jahren rückläufig.<p /> <p>Language: de</p>",
language="de",
issn="0303-4259",
doi="10.1055/a-0961-2371",
url="http://dx.doi.org/10.1055/a-0961-2371"
}