@article{ref1,
title="Firefighter's acute inflammatory response to wildfire suppression",
journal="Journal of Occupational and Environmental Medicine",
year="2019",
author="Main, Luana C. and Wolkow, Alexander P. and Tait, Jamie L. and Gatta, Paul Della and Raines, Jenni and Snow, Rodney and Aisbett, Brad",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="OBJECTIVES: The purpose of this study was to determine the inflammatory response to a 12-hour wildfire suppression shift, in firefighters attending the &quot;Black Saturday&quot; natural disaster. <br><br>METHODS: Thirty-eight male volunteer firefighters provided venous blood samples before and after a 12-hour firefighting shift. Pre- to post-shift changes in pro-inflammatory (Interleukin [IL]-1β, IL-2, IL-6, IL-8, IL-12P70, granulocyte macrophage-colony stimulating factor [GM-CSF], tumor necrosis factor-alpha [TNF-α], interferon-gamma [IFNγ]), and anti-inflammatory (IL-4, IL-5, IL-7, IL-10, IL-13) cytokines were measured with paired sample t tests, or Wilcoxon t tests for non-parametric data. <br><br>RESULTS: Interleukin (IL)-6 (P = 0.003) and IL-8 (P = 0.017) were significantly increased following 12-hours of wildfire suppression. There was also a significant decrease in IL-10 (P = 0.021). <br><br>CONCLUSIONS: The observed acute inflammatory response may have resulted from multiple stressors including physical exertion, thermal strain, or smoke inhalation experienced during the shift, and may be a necessary response for the body to adapt to stressor exposure.<p /> <p>Language: en</p>",
language="en",
issn="1076-2752",
doi="10.1097/JOM.0000000000001775",
url="http://dx.doi.org/10.1097/JOM.0000000000001775"
}